Comparison of MTB specific IP-10 responses, mitogen specific IP-10 responses and MTB specific to mitogen specific ratio among household contacts and active TB cases.

<p>Box graphs comparing medians A) MTB antigen specific IP-10 levels, B) mitogen specific IP-10 levels, and C) MTB specific to mitogen specific ratio in uninfected contacts, LTBI contacts and active TB cases. IP-10 was measured in QFN supernatants from uninfected contacts (negative to both TST and by QFN), LTBI contacts (positive in both TST and QFN), and active TB cases at baseline. Baseline uninfected contacts, n = 66; latently infected contacts, n = 62; active TB cases n = 102. Pairwise comparisons were made using the Mann-Whitney <i>U</i> test