<p>The D816V mutation in the catalytic domain of the c-Kit receptor downstream tyrosine kinase in peripheral blood mononuclear cells (by M. Niedoszytko).</p
Oncogenic mutants of c-Kit are often found in mastocytosis, gastrointestinal stromal tumors and acut...
Mast cell (MC) differentiation, survival, and activation are controlled by the membrane tyrosine kin...
grantor: University of TorontoThe recent identification a number of activating Kit mutants...
The c-kit receptor tyrosine kinase (KIT) is constitutively activated by naturally occurring mutation...
The c-kit pruto-oncogene encodes a receptor tyrosine kinase that is known to play a crucial role in ...
The receptor tyrosine kinase c-Kit plays a critical role in hematopoiesis and gain-of-function mutat...
Activating mutations of codon 816 of the Kit gene have been implicated in malignant cell growth of a...
Oncogenic c-Kit mutations have been shown to display ligand-independent receptor activation and cell...
The colony stimulating factor-1 receptor (CSF-1R) and the stem cell factor receptor KIT, type III re...
grantor: University of TorontoAn activating mutation (DY814) located in the catalytic doma...
The type III receptor tyrosine kinase (RTK) KIT plays a crucial role in the transmission of cellular...
The colony stimulating factor-1 receptor (CSF-1R) and the stem cell factor receptor KIT, type III re...
A subset of AML-M2/M4Eo patients has been shown to carry c-kit mutations suggesting that myelomonobl...
Together with its ligand, stem cell factor, the receptor tyrosine kinase c-Kit is a key controlling ...
Stem cell factor (SCF) binds the receptor tyrosine kinase c-Kit and is critical for normal hematopoi...
Oncogenic mutants of c-Kit are often found in mastocytosis, gastrointestinal stromal tumors and acut...
Mast cell (MC) differentiation, survival, and activation are controlled by the membrane tyrosine kin...
grantor: University of TorontoThe recent identification a number of activating Kit mutants...
The c-kit receptor tyrosine kinase (KIT) is constitutively activated by naturally occurring mutation...
The c-kit pruto-oncogene encodes a receptor tyrosine kinase that is known to play a crucial role in ...
The receptor tyrosine kinase c-Kit plays a critical role in hematopoiesis and gain-of-function mutat...
Activating mutations of codon 816 of the Kit gene have been implicated in malignant cell growth of a...
Oncogenic c-Kit mutations have been shown to display ligand-independent receptor activation and cell...
The colony stimulating factor-1 receptor (CSF-1R) and the stem cell factor receptor KIT, type III re...
grantor: University of TorontoAn activating mutation (DY814) located in the catalytic doma...
The type III receptor tyrosine kinase (RTK) KIT plays a crucial role in the transmission of cellular...
The colony stimulating factor-1 receptor (CSF-1R) and the stem cell factor receptor KIT, type III re...
A subset of AML-M2/M4Eo patients has been shown to carry c-kit mutations suggesting that myelomonobl...
Together with its ligand, stem cell factor, the receptor tyrosine kinase c-Kit is a key controlling ...
Stem cell factor (SCF) binds the receptor tyrosine kinase c-Kit and is critical for normal hematopoi...
Oncogenic mutants of c-Kit are often found in mastocytosis, gastrointestinal stromal tumors and acut...
Mast cell (MC) differentiation, survival, and activation are controlled by the membrane tyrosine kin...
grantor: University of TorontoThe recent identification a number of activating Kit mutants...