Assessment of motor performance using wheel running apparatus.

<p>[A] Total number of wheel rotations per hour upon wheel running for six consecutive days. The number of wheel rotations gradually increased but showed no significant difference between WT and Caspr3-KO mice. [B] Number of running errors (swings) per 1,000 rotations during wheel running training. No significant differences were observed in the numbers of running errors between WT and Caspr3-KO mice. [C] The number of running errors per 1,000 rotations, expressed as a percentage of the error score on day 1, on days 2–6. The errors of WT and Caspr3-KO mice decreased during the days of training, and there was no significant difference between the two genotypes. Error bars represent SEM. n = 14 (WT mice), n = 12 (Caspr3-KO mice).