Differential expression of epithelial and mesenchymal markers in TC1 and TC2 tumors.

<p>(A) Unsupervised hierarchical clustering of global gene expression data of normal prostates (NP), hyperplastic prostates (HP) and TC1 and TC2 prostate tumors. (B) The relative mRNA expression levels of <i>CK8</i>, <i>E-cadherin</i>, <i>Snail</i> and <i>Fibronectin</i> in NP (n = 3), HP (n = 3), TC1 (n = 3) and TC2 (n = 6) as detected in the expression arrays. Indicated gene expressions were plotted relative to the housekeeping gene <i>Hprt</i>. (C) Representative Q-PCR analysis of <i>Snail</i> and <i>E-cadherin</i> expression. Expression of <i>Hprt</i> was used as Q-PCR reference. Data are presented as mean +/- SE. * <i>p</i> < 0.05, by Mann-Whitney two tailed test.