Chronic alcoholic myopathy affects up to two-thirds of all alcohol misusers and is characterized by selective atrophy of Type If (glycolytic, fast-twitch, anaerobic) fibers. In contrast, the Type I fibers (oxidative, slow-twitch, aerobic) are relatively protected. Alcohol increases the concentration of cholesterol hydroperoxides and malondialdehyde-protein adducts, though protein-carbonyl concentration levels do not appear to be overtly increased and may actually decrease in some studies. In alcoholics, plasma concentrations of a-tocopherol may be reduced in myopathic patients. However, a-tocopherol supplementation has failed to prevent either the loss of skeletal muscle protein or the reductions in protein synthesis in alcohol-dosed animal...
SUMMARY The comparative electrophysiologic, histochemical, and biochemical investigation of the ante...
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan....
Background: Chronic alcohol ingestion may cause severe biochemical and pathophysiological derangemen...
Alcohol consumption induces a dose-dependent noxious effect on skeletal muscle, leading to progressi...
Chronic alcohol muscle disease is characterized by reduced skeletal muscle mass precipitated by acut...
Background: Muscle weakness and structural changes in striated skeletal muscle are common in persons...
Background Chronic alcoholic myopathy is characterised by reduced muscle strength and structural cha...
One hundred and fifty-one inpatients with a history of chronic heavy alcohol intake were examined fo...
Background: Excessive intake of alcohol is often associated with low or subnormal levels of vitamin ...
Abstract — Aims: Skeletal muscle appears to be susceptible to chronic and acute excess alcohol intak...
Abstract — Aims: Chronic myopathy has been described in alcoholics, characterized by atrophy of type...
Background Chronic alcohol ingestion may cause severe biochemical and pathophysiological derangement...
© 2019 Elsevier Inc. Protein synthesis and autophagy are regulated by cellular ATP content. We teste...
Aims: Previous immunohistochemical studies have shown that the post-translational formation of aldeh...
Previous studies have shown that chronic heavy alcohol consumption and consumption of a high-fat (HF...
SUMMARY The comparative electrophysiologic, histochemical, and biochemical investigation of the ante...
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan....
Background: Chronic alcohol ingestion may cause severe biochemical and pathophysiological derangemen...
Alcohol consumption induces a dose-dependent noxious effect on skeletal muscle, leading to progressi...
Chronic alcohol muscle disease is characterized by reduced skeletal muscle mass precipitated by acut...
Background: Muscle weakness and structural changes in striated skeletal muscle are common in persons...
Background Chronic alcoholic myopathy is characterised by reduced muscle strength and structural cha...
One hundred and fifty-one inpatients with a history of chronic heavy alcohol intake were examined fo...
Background: Excessive intake of alcohol is often associated with low or subnormal levels of vitamin ...
Abstract — Aims: Skeletal muscle appears to be susceptible to chronic and acute excess alcohol intak...
Abstract — Aims: Chronic myopathy has been described in alcoholics, characterized by atrophy of type...
Background Chronic alcohol ingestion may cause severe biochemical and pathophysiological derangement...
© 2019 Elsevier Inc. Protein synthesis and autophagy are regulated by cellular ATP content. We teste...
Aims: Previous immunohistochemical studies have shown that the post-translational formation of aldeh...
Previous studies have shown that chronic heavy alcohol consumption and consumption of a high-fat (HF...
SUMMARY The comparative electrophysiologic, histochemical, and biochemical investigation of the ante...
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan....
Background: Chronic alcohol ingestion may cause severe biochemical and pathophysiological derangemen...