<p>Expected number of subclonal and clonal mutations for different values of <i>δ</i> = <i>d</i>/<i>b</i>.</p
(A) Cumulative distribution of codon mutability of silent (green), nonsense (red) and missense (blue...
The average and the modal number of chromosome copies in the limiting distribution of on viable cel...
<p>Distribution of the growth phenotype of all 348,300 single gene knock-out mutants.</p
<p>The expected frequency of mutants according to geometric distribution is shown in bold italics.</...
<p><sup>1</sup>b, Mutations only found in isolate b compared to isolate a; c, mutations only found i...
<p> </p><p> </p><p> </p><p>The expected mutation cou...
<p>The frequency of KRAS, BRAF and PIK3CA mutations according to different patterns.</p
<p>(a) Prediction of average number of accumulated mutations per diploid human cell as a function of...
A) Mean clonal and subclonal mutations found in each tumor type. For each tumor type we report: mean...
<p>Comparison of the incidences of SMAD4 mutations across different molecular subtypes.</p
<p>Tumor zygosity predictions of somatic mutations in 20,182 clinical samples.</p
<p>Clonal numbers and variant allele frequencies for driver mutations in 15 WGS metastatic tumors.</...
<p>A: the number of sequences that drove the cancerous state.</p><p>B: the number of sequences that ...
Number of accumulated gene mutations for serrated adenocarcinomas in normal tissue and adenoma-adjac...
<p>Distribution of pathogenic mutations reported out in first 3,000 patient samples referred for BRC...
(A) Cumulative distribution of codon mutability of silent (green), nonsense (red) and missense (blue...
The average and the modal number of chromosome copies in the limiting distribution of on viable cel...
<p>Distribution of the growth phenotype of all 348,300 single gene knock-out mutants.</p
<p>The expected frequency of mutants according to geometric distribution is shown in bold italics.</...
<p><sup>1</sup>b, Mutations only found in isolate b compared to isolate a; c, mutations only found i...
<p> </p><p> </p><p> </p><p>The expected mutation cou...
<p>The frequency of KRAS, BRAF and PIK3CA mutations according to different patterns.</p
<p>(a) Prediction of average number of accumulated mutations per diploid human cell as a function of...
A) Mean clonal and subclonal mutations found in each tumor type. For each tumor type we report: mean...
<p>Comparison of the incidences of SMAD4 mutations across different molecular subtypes.</p
<p>Tumor zygosity predictions of somatic mutations in 20,182 clinical samples.</p
<p>Clonal numbers and variant allele frequencies for driver mutations in 15 WGS metastatic tumors.</...
<p>A: the number of sequences that drove the cancerous state.</p><p>B: the number of sequences that ...
Number of accumulated gene mutations for serrated adenocarcinomas in normal tissue and adenoma-adjac...
<p>Distribution of pathogenic mutations reported out in first 3,000 patient samples referred for BRC...
(A) Cumulative distribution of codon mutability of silent (green), nonsense (red) and missense (blue...
The average and the modal number of chromosome copies in the limiting distribution of on viable cel...
<p>Distribution of the growth phenotype of all 348,300 single gene knock-out mutants.</p
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