Boosting with Ad-encoded flagellin via intramuscular or intranasal routes caused transient morbidity in mice.

<p>Mice were primed twice with DNA vaccine via the IM route, and some groups were boosted either IM or IN with Ad vaccine 3 weeks later as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148701#pone.0148701.t001" target="_blank">Table 1</a>, Body mass was monitored post-systemic (A) or mucosal (B) boosting with Ad vaccines, or post-DNA priming (C) Data shown represent percentage of average change in body mass ± SEM per group for 5 individual mice within each group (*<i>p</i> < 0.05 vs 85B/85B group). Representative data from one of two independent experiments are shown (n = 5).