A Hierarchical Self-Assembly System Built Up from Preorganized Tripodal Helical Metal Complexes

The hierarchical organization strategy has realized elaborate supramolecular structures that are difficult to achieve by a one-pot thermodynamically driven self-assembly. Self-assembly via Schiff base formation of the preorganized tripodal helical unit <b>2</b>²⁺, which is composed of the tris­(bipyridyl) ligand <b>1</b> and octahedral metal ion (Ru^II and Fe^II), lead to two supramolecular structures, i.e., a macrobicyclic dimer and an interlocked helicate. Notably, the interlocked helicate had a unique motif with an elongated shape (∼58 Å) and linearly aligned metal centers with homochiral configurations (all-Δ or all-Λ), which shows potential for allosteric regulation based on the long-range transmittance of the structural information