Histological sections of testicular tissue taken from mice in the four groups at different time points.

<p>Hematoxylin & Eosin staining is shown. A-D Numbers 1–5 refer to the day after treatment on which the samples were taken, where 1 = day 14, 2 = day 21, 3 = day 28, 4 = day 35 and 5 = day 70. A1–A5) The negative control group mice were treated with 50% DMSO at corresponding time points. B1–B5) Testis tissue sections from mice in the 4 mg/kg/side testis-treated group at corresponding time points. C1–C5) Testis tissue sections from mice in the 6 mg/kg/side testis-treated group at corresponding time points. D1–D5) Testis tissue sections from mice in the 40 mg/kg I.P. injection group. Scale bars(A = 100μm, B,C,D = 50 μm).