Overexpression of DN-RAB18 (S22N) mildly impairs the neuronal migration at E18.5. A Representative coronal section showing migration of transfected neurons 4 d after electroporated at E14.5 with GFP plasmid together with indicated constructs. Scale bar: 100 μm. B Quantitative analysis of GFP positive neurons in different cortical regions in A. Data represent the mean ± SEM (n = 3); * p < 0.05 versus control; t test. (PDF 78 kb
GFP expression by lenti-GFP-transduced hNSCs. Proliferating lenti-GFP-transduced hNSCs form neurosph...
Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...
Steady state levels of p27kip1 are not significantly altered in Rp58(+/−) and Rp58(−/−) mutant mice ...
There is no apparently changed after overexpression of RAB18 in cortical neuronal migration. A Repre...
The distributions of neurons do not have apparent differences after suppression of RAB3GAP2 at E18.5...
Figure S1. Immunostaining of cortical neurons transfected with Rab35 mutants. Representative images ...
Background: Loss of function mutations in RAB18, has been identified in patients with the human neur...
Figure S3. Localization of Rab35 WT and phosphomutants. (a) HEK-293 cells were transfected with V5-t...
Figure S1. Rac1 mutant peptides have high penetration due to the TAT sequence. (A-C) Representative ...
Figure S1. Purity of primary microglia cultures. Figure S2. Par1b/MARK2 is expressed in microglia. F...
Forced expression of p27kip1 enhances radial migration and alters the morphological characteristics ...
Figure S1. Neuropathology of case 3. The neuropathological study on brain sample from case 3 showed ...
BBB permeability of control and Cstb −/− mice. (A) Levels of sodium fluorescein (NaF) in the brain o...
Figure S2. Representative images of Aβ deposition in the brains of APP/PS1 transgenic mice. Immunohi...
VPS35 interaction with GluA1 and GluA2. (A) Co-immunostaining analysis of endogenous VPS35 with GFP-...
GFP expression by lenti-GFP-transduced hNSCs. Proliferating lenti-GFP-transduced hNSCs form neurosph...
Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...
Steady state levels of p27kip1 are not significantly altered in Rp58(+/−) and Rp58(−/−) mutant mice ...
There is no apparently changed after overexpression of RAB18 in cortical neuronal migration. A Repre...
The distributions of neurons do not have apparent differences after suppression of RAB3GAP2 at E18.5...
Figure S1. Immunostaining of cortical neurons transfected with Rab35 mutants. Representative images ...
Background: Loss of function mutations in RAB18, has been identified in patients with the human neur...
Figure S3. Localization of Rab35 WT and phosphomutants. (a) HEK-293 cells were transfected with V5-t...
Figure S1. Rac1 mutant peptides have high penetration due to the TAT sequence. (A-C) Representative ...
Figure S1. Purity of primary microglia cultures. Figure S2. Par1b/MARK2 is expressed in microglia. F...
Forced expression of p27kip1 enhances radial migration and alters the morphological characteristics ...
Figure S1. Neuropathology of case 3. The neuropathological study on brain sample from case 3 showed ...
BBB permeability of control and Cstb −/− mice. (A) Levels of sodium fluorescein (NaF) in the brain o...
Figure S2. Representative images of Aβ deposition in the brains of APP/PS1 transgenic mice. Immunohi...
VPS35 interaction with GluA1 and GluA2. (A) Co-immunostaining analysis of endogenous VPS35 with GFP-...
GFP expression by lenti-GFP-transduced hNSCs. Proliferating lenti-GFP-transduced hNSCs form neurosph...
Figure S1. Aβ1–42 induces ER stress and upregulates MANF expression in primarily cultured rat neuron...
Steady state levels of p27kip1 are not significantly altered in Rp58(+/−) and Rp58(−/−) mutant mice ...