Additional file 1: Figure S1. of X chromosome-wide analysis identifies DNA methylation sites influenced by cigarette smoking

Distribution of mean β-values of all X chromosomal sites in males (A) and females (B). Figure S2. Quantile-quantile plot comparing observed p-values to expected p-values of all CpG sites on the X chromosome from the epigenetic association study with current smoking status. Dashed line indicates 95 % CI for distribution of expected p-values. Figure S3. Manhattan plot of all CpG sites on the X chromosome and their association with current smoking status. The red line represents a FDR significance level of 0.05. Figure S4. Forest plots of the smoking-related DNAm sites in males from the discovery and three replication samples using M-value. A: cg07764473 (BCOR). B: cg21380860 (TSC22D3). (PDF 703 kb