Comparison between IDO1-KO and IFN-γ-KO mice after CFA injection.

<p>CFA was injected into BALB/c WT, IDO1-KO and IFN-γ-KO mice at day 0. Mice were sacrificed at day 21 after immunization. <b>A</b>. Average ± SD percent body weight change. <b>B.</b> Spleen weight as a percentage of total body weight. <b>C.</b> Blood platelet and neutrophil counts as measured by hematology analyzer. <b>D.</b> Percentage of live CD3^- CD49b⁺ CD122⁺ natural killer cells of total live spleen cells. B-D: Symbols represent individual mice with corresponding group median. Data from one experiment. NI, noninjected; CFA, complete Freund’s adjuvant; NK, natural killer.