<p><b>A) Boxplots showing protein concentrations ranges in CSF from 72 individuals without neurological disorders.</b> The concentration ranges between the upper and lower limits of detection for each marker are shown in grey. The numbers below and above the boxplots show the number of patient samples (out of the total 72) that are outside the detection limits. <b>B) Performance measures for each protein assay.</b> The 1<sup>st</sup>, 2<sup>nd</sup> (median) and 3<sup>rd</sup> quartile values of the robust % CV. The numbers of detectable samples out of a total of 72 samples are found at the bottom line for each marker.</p
The analytical, intra- and inter-individual components of biological variation were estimated for pr...
<p>Concentration (median and range) for individual protein biomarkers measured in the serum of cance...
Samples are categorised by whether they came from a) healthy controls, who did not develop any infec...
<p><sup>*</sup>: Concentrations in ng/mL.</p><p>Protein levels in the different groups are presented...
a). Lower and upper detectable limits and the upper CV limit of the protein biomarkers included. Val...
<p>(A) Rates of positivity of 14-3-3 protein in the CSF of 141 gPrD patients. The number of patients...
a<p>If indicated, CSF was concentrated using Millipore Amicon Ultra 3 kDa filters.</p>b<p>Only linea...
Dynamics of log protein levels for the 15 proteins with nominal p-values <0.05 for change either fro...
<p>A. Distribution of inter-individual variations of CSF and urine are shown in a box plot. The inte...
Cerebrospinal fluid is investigated in biomarker studies for various neurological disorders of the c...
Cerebrospinal fluid is investigated in biomarker studies for various neurological disorders of the c...
A: This figure provides twelve Venn diagrams, one for each human subject. Only proteins that were fo...
<p><sup>*</sup>CF severity: a semi-quantitative evaluation of individual patients by the clinicians,...
<p><sup>*</sup>CF severity: a semi-quantitative evaluation of individual patients by the clinicians,...
<p>Protein concentration of the cerebrospinal fluid (CSF)-derived proteins from the seven points alo...
The analytical, intra- and inter-individual components of biological variation were estimated for pr...
<p>Concentration (median and range) for individual protein biomarkers measured in the serum of cance...
Samples are categorised by whether they came from a) healthy controls, who did not develop any infec...
<p><sup>*</sup>: Concentrations in ng/mL.</p><p>Protein levels in the different groups are presented...
a). Lower and upper detectable limits and the upper CV limit of the protein biomarkers included. Val...
<p>(A) Rates of positivity of 14-3-3 protein in the CSF of 141 gPrD patients. The number of patients...
a<p>If indicated, CSF was concentrated using Millipore Amicon Ultra 3 kDa filters.</p>b<p>Only linea...
Dynamics of log protein levels for the 15 proteins with nominal p-values <0.05 for change either fro...
<p>A. Distribution of inter-individual variations of CSF and urine are shown in a box plot. The inte...
Cerebrospinal fluid is investigated in biomarker studies for various neurological disorders of the c...
Cerebrospinal fluid is investigated in biomarker studies for various neurological disorders of the c...
A: This figure provides twelve Venn diagrams, one for each human subject. Only proteins that were fo...
<p><sup>*</sup>CF severity: a semi-quantitative evaluation of individual patients by the clinicians,...
<p><sup>*</sup>CF severity: a semi-quantitative evaluation of individual patients by the clinicians,...
<p>Protein concentration of the cerebrospinal fluid (CSF)-derived proteins from the seven points alo...
The analytical, intra- and inter-individual components of biological variation were estimated for pr...
<p>Concentration (median and range) for individual protein biomarkers measured in the serum of cance...
Samples are categorised by whether they came from a) healthy controls, who did not develop any infec...