<p>A) On the right, the orange phenotype is over-represented relative to the null model: The red genotype in the centre has more orange neighbours than would be expected by the global frequency of orange. B) The phenotypes that appear in the mutational neighbourhood of two neutral neighbours are expected to be more similar (right) than two non-neighbouring genotypes of the same phenotype (left).</p
<p>The 98 quantative traits are classified into clusters inferred from genetic correlations between ...
<p>The red line is a fitted linear regression, and the red tube represents its 95-confidence interva...
Among the most fundamental features shared by all organisms is the mapping of information encoded in...
<p>Phenotypes are represented by colours, genotypes as nodes and mutations as edges. A) Each colour ...
<p>We present results for the three GP maps: A) RNA20, B) <i>S</i><sub>3,8</sub> and C) HP5x5. We pi...
Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to s...
a) Genotypes distribution of each subject was compared with those of all the other subjects. Such an...
<p>The rates of mutation between phenotype <i>i</i> and phenotype <i>j</i> in simulations is nearly ...
<p>upper side triangle are phenotypic correlations, lower side triangle are genetic correlations wit...
<p>Genetic correlations (above diagonal) and individual-specific environmental correlations (below d...
<p>A) The phenotype robustness <i>ρ</i><sub><i>p</i></sub> is plotted as a function of frequency <i>...
Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to s...
<p>(a), (b) The more robust phenotype has higher structural diversity in its 1-neighbourhood. We obs...
<p>a) Illustrating reciprocal sign epistasis. When there is no epistasis the combined effects of two...
<p>The figure shows the frequency spectra of nonsynonymous (red) and synonymous (black) mutations am...
<p>The 98 quantative traits are classified into clusters inferred from genetic correlations between ...
<p>The red line is a fitted linear regression, and the red tube represents its 95-confidence interva...
Among the most fundamental features shared by all organisms is the mapping of information encoded in...
<p>Phenotypes are represented by colours, genotypes as nodes and mutations as edges. A) Each colour ...
<p>We present results for the three GP maps: A) RNA20, B) <i>S</i><sub>3,8</sub> and C) HP5x5. We pi...
Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to s...
a) Genotypes distribution of each subject was compared with those of all the other subjects. Such an...
<p>The rates of mutation between phenotype <i>i</i> and phenotype <i>j</i> in simulations is nearly ...
<p>upper side triangle are phenotypic correlations, lower side triangle are genetic correlations wit...
<p>Genetic correlations (above diagonal) and individual-specific environmental correlations (below d...
<p>A) The phenotype robustness <i>ρ</i><sub><i>p</i></sub> is plotted as a function of frequency <i>...
Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to s...
<p>(a), (b) The more robust phenotype has higher structural diversity in its 1-neighbourhood. We obs...
<p>a) Illustrating reciprocal sign epistasis. When there is no epistasis the combined effects of two...
<p>The figure shows the frequency spectra of nonsynonymous (red) and synonymous (black) mutations am...
<p>The 98 quantative traits are classified into clusters inferred from genetic correlations between ...
<p>The red line is a fitted linear regression, and the red tube represents its 95-confidence interva...
Among the most fundamental features shared by all organisms is the mapping of information encoded in...