EcoHIV infection activates platelets indirectly.

<p>Whole blood was collected from wild-type C57BL/6 J (WT) mice (n = 3) and treated with 10 μM ADP or EcoHIV (1.0x10⁵ pg p24) for the indicated time periods (each group n = 3) <i>in vitro</i>. Activated platelets (CD61+ CD62P+) were then quantified by flow cytometry. The percentage of CD62P+ platelets in EcoHIV treated blood was comparable to non-treated (NT) blood, indicating the inability of EcoHIV in directly activating platelets.