<p>β2GPI -/- mice treated with control sustained the same myocardial infarction size on 1% TTC staining as WT mice. Domain V (n = 6) protects β2GPI -/- mice from cardiac IRI compared with control (n = 11). Reconstitution with rmβ2GPI (n = 6) resulted in similar infarction size to control mice. Individual points represent infarct size as a % of AAR of a single mouse. The horizontal line for each study group represents the mean. NS = not significant.</p
<p>(A) Heart weight (HW) normalized to body weight (BW) in tTA and NLK DTG mice at the indicated age...
<p>(A) Cross sectional area in heart sections from WT and SGK1-/- mice. Area was measured in ≥10 dis...
<p>(<b>A</b>) Representative photomicrographs of in situ detection of DNA fragments (TUNEL) in myoca...
<p>(A) Rag-1 -/- mice were treated with saline or pooled murine IgM prior to IRI. The mice treated w...
<p>(A) Representative photographs of TTC-stained mouse heart sections obtained from listed groups 24...
<p>Infarct size is expressed as a percentage of the region at risk of infarction. Data are expressed...
<p>NT = No treatment. rhβ2GPI = recombinant human β2GPI. Domain V = recombinant human Domain V. Hori...
<p><b>a</b>. Gα<sub>i2</sub><sup>+/+</sup> (n = 6) and Gα<sub>i2</sub><sup>-/-</sup> (n = 7) mice we...
<p><b>a</b>. Gα<sub>i3</sub><sup>+/+</sup> (n = 7) and Gα<sub>i3</sub><sup>-/-</sup> (n = 6) mice we...
<p>(<b>A</b>) Representative images of Evans blue and triphenyltetrazolium chloride (TTC) staining i...
<p>When compared with the corresponding wild-type mice, infarct scar size (Masson's trichrome stain)...
<p><b>A-B</b>: The representative E18.5 mouse hearts from the control (A) and PGDM (B) groups. <b>C-...
<p>MI was induced in male and female C57BL/6 mice by ligation of LAD, and immediately i.p. injected ...
<p><b>A)</b> Comparison of UNC5B protein expression in <i>UNC5B<sup>+/−</sup></i> and WT animals in ...
<p>Infarct size in VEGF-A upregulated (shRNA) and in control (shRNA Control) groups measured using M...
<p>(A) Heart weight (HW) normalized to body weight (BW) in tTA and NLK DTG mice at the indicated age...
<p>(A) Cross sectional area in heart sections from WT and SGK1-/- mice. Area was measured in ≥10 dis...
<p>(<b>A</b>) Representative photomicrographs of in situ detection of DNA fragments (TUNEL) in myoca...
<p>(A) Rag-1 -/- mice were treated with saline or pooled murine IgM prior to IRI. The mice treated w...
<p>(A) Representative photographs of TTC-stained mouse heart sections obtained from listed groups 24...
<p>Infarct size is expressed as a percentage of the region at risk of infarction. Data are expressed...
<p>NT = No treatment. rhβ2GPI = recombinant human β2GPI. Domain V = recombinant human Domain V. Hori...
<p><b>a</b>. Gα<sub>i2</sub><sup>+/+</sup> (n = 6) and Gα<sub>i2</sub><sup>-/-</sup> (n = 7) mice we...
<p><b>a</b>. Gα<sub>i3</sub><sup>+/+</sup> (n = 7) and Gα<sub>i3</sub><sup>-/-</sup> (n = 6) mice we...
<p>(<b>A</b>) Representative images of Evans blue and triphenyltetrazolium chloride (TTC) staining i...
<p>When compared with the corresponding wild-type mice, infarct scar size (Masson's trichrome stain)...
<p><b>A-B</b>: The representative E18.5 mouse hearts from the control (A) and PGDM (B) groups. <b>C-...
<p>MI was induced in male and female C57BL/6 mice by ligation of LAD, and immediately i.p. injected ...
<p><b>A)</b> Comparison of UNC5B protein expression in <i>UNC5B<sup>+/−</sup></i> and WT animals in ...
<p>Infarct size in VEGF-A upregulated (shRNA) and in control (shRNA Control) groups measured using M...
<p>(A) Heart weight (HW) normalized to body weight (BW) in tTA and NLK DTG mice at the indicated age...
<p>(A) Cross sectional area in heart sections from WT and SGK1-/- mice. Area was measured in ≥10 dis...
<p>(<b>A</b>) Representative photomicrographs of in situ detection of DNA fragments (TUNEL) in myoca...