<p>The mean final epidemic size for two coupled cities 〈<i>E</i>〉 is plotted as a function of fractional vaccine allocation to city B and coupling <i>f</i><sub>AB</sub> for varying amounts of available vaccine at <i>τ</i> = 1 day (panel A) and <i>τ</i> = 10 days (panel B). City A has 39 initial susceptibles and 1 infective; city B has 40 initial susceptibles. The recovery rate <i>γ</i> = 0.15 and the reproductive number <i>r</i><sub>0</sub> = 2.</p
<p>Drift opportunity for scenario C with targeted distribution of a vaccine stockpile sufficient for...
<p><b>Upper panels:</b> drift opportunity relative to an unimpeded epidemic as a function of general...
Limited production capacity and delays inherent in vaccine development are major hurdles to the wide...
<p>The stochastic combined mean final epidemic size 〈<i>E</i>〉 as a function of the fractional alloc...
<p>The optimal fraction of total vaccine allocated to city B is plotted as a function of available v...
Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infecti...
<p>Lines show the proportion of the host population infected at a particular time, and each panel sh...
<p>Given population density, 60 simulation replicates were run for each vaccination diffusion rate <...
<p>The difference in stochastic mean final epidemic size 〈<i>E</i>〉 between worst-case and optimal p...
<p>A. Conditional on persistence, estimates of <i>R</i><sub>0</sub> improve as the outbreak progress...
Timing is of crucial importance for successful vaccination. To avoid a large outbreak, vaccines are ...
<p>Figures A and B illustrate results for the stochastic model with <i>r</i><sub>0</sub> = 5 and <i>...
<p>The solid lines in Figures A and B illustrate the optimal fraction of the available vaccine alloc...
<p>The difference in stochastic mean final epidemic size 〈<i>E</i>〉 between worst-case and optimal p...
The value of μ which minimizes the fatalities in country A is termed the ‘optimal policy’. The simul...
<p>Drift opportunity for scenario C with targeted distribution of a vaccine stockpile sufficient for...
<p><b>Upper panels:</b> drift opportunity relative to an unimpeded epidemic as a function of general...
Limited production capacity and delays inherent in vaccine development are major hurdles to the wide...
<p>The stochastic combined mean final epidemic size 〈<i>E</i>〉 as a function of the fractional alloc...
<p>The optimal fraction of total vaccine allocated to city B is plotted as a function of available v...
Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infecti...
<p>Lines show the proportion of the host population infected at a particular time, and each panel sh...
<p>Given population density, 60 simulation replicates were run for each vaccination diffusion rate <...
<p>The difference in stochastic mean final epidemic size 〈<i>E</i>〉 between worst-case and optimal p...
<p>A. Conditional on persistence, estimates of <i>R</i><sub>0</sub> improve as the outbreak progress...
Timing is of crucial importance for successful vaccination. To avoid a large outbreak, vaccines are ...
<p>Figures A and B illustrate results for the stochastic model with <i>r</i><sub>0</sub> = 5 and <i>...
<p>The solid lines in Figures A and B illustrate the optimal fraction of the available vaccine alloc...
<p>The difference in stochastic mean final epidemic size 〈<i>E</i>〉 between worst-case and optimal p...
The value of μ which minimizes the fatalities in country A is termed the ‘optimal policy’. The simul...
<p>Drift opportunity for scenario C with targeted distribution of a vaccine stockpile sufficient for...
<p><b>Upper panels:</b> drift opportunity relative to an unimpeded epidemic as a function of general...
Limited production capacity and delays inherent in vaccine development are major hurdles to the wide...