α-Synuclein immunohistochemistry. Representative substantia nigra photomicrographs stained for anti-human-α-synuclein. No staining was observed throughout the brain. ×10 magnification. Scale bar, 100 μm. (PDF 1.65 mb
Morphological analysis of striatal microglia by Iba1 immunostaining. (A) Representative high-magnifi...
B lymphocytes do not infiltrate the midbrain of WTS+ Rag2+/+ mice. (A) WTS+ Rag2+/+ and WTS+ Rag2−/−...
Figure S3. Determination of protein concentration of α-syn in C57BL/6 mouse brain, Standard curve of...
MHC II, CD4, and mouse IgG immunohistochemistry. A, B Representative photomicrographs of SN brain se...
Figure S1, related to Fig. 2. Delivery of TLR2 overexpression lentiviral vectors into mouse model of...
Levels of α-syn immunoreactivity in individual oligodendroglial cells in the brains of MBP-α-syn tg ...
Figure S3. Antigen-presenting MHC-IIir microglia are not associated with peak of intraneuronal inclu...
Co-IP studies confirm the α-synuclein-SOD1 binding. (A) α-Synuclein immunoprecipitation of co-transf...
Figure S3. Low levels of contaminating endotoxins and proteins in the recombinant synuclein preparat...
Figure S1. NO production in αSYN and TLR4-inhibitor treated astrocytes. Primary astrocytes were trea...
Figure S1. Widespread brain expression of human αS in M20+/−and M83+/− mice. Immunohistochemistry sh...
Figure S2. Seeding activities of serial dilutions of sarkosyl-insoluble fractions from brains of α-s...
Figure S1. Isolation and characterization of astrocyte cultures from transgenic (Tg) mice. Figure S2...
MHCII staining in IL-6 expressing mice injected with αSyn fibrils or PBS. Mice were injected at neon...
Co-localization of α-synuclein and SOD1 in wt mouse brain. Representative images of C57Bl/6 wt mouse...
Morphological analysis of striatal microglia by Iba1 immunostaining. (A) Representative high-magnifi...
B lymphocytes do not infiltrate the midbrain of WTS+ Rag2+/+ mice. (A) WTS+ Rag2+/+ and WTS+ Rag2−/−...
Figure S3. Determination of protein concentration of α-syn in C57BL/6 mouse brain, Standard curve of...
MHC II, CD4, and mouse IgG immunohistochemistry. A, B Representative photomicrographs of SN brain se...
Figure S1, related to Fig. 2. Delivery of TLR2 overexpression lentiviral vectors into mouse model of...
Levels of α-syn immunoreactivity in individual oligodendroglial cells in the brains of MBP-α-syn tg ...
Figure S3. Antigen-presenting MHC-IIir microglia are not associated with peak of intraneuronal inclu...
Co-IP studies confirm the α-synuclein-SOD1 binding. (A) α-Synuclein immunoprecipitation of co-transf...
Figure S3. Low levels of contaminating endotoxins and proteins in the recombinant synuclein preparat...
Figure S1. NO production in αSYN and TLR4-inhibitor treated astrocytes. Primary astrocytes were trea...
Figure S1. Widespread brain expression of human αS in M20+/−and M83+/− mice. Immunohistochemistry sh...
Figure S2. Seeding activities of serial dilutions of sarkosyl-insoluble fractions from brains of α-s...
Figure S1. Isolation and characterization of astrocyte cultures from transgenic (Tg) mice. Figure S2...
MHCII staining in IL-6 expressing mice injected with αSyn fibrils or PBS. Mice were injected at neon...
Co-localization of α-synuclein and SOD1 in wt mouse brain. Representative images of C57Bl/6 wt mouse...
Morphological analysis of striatal microglia by Iba1 immunostaining. (A) Representative high-magnifi...
B lymphocytes do not infiltrate the midbrain of WTS+ Rag2+/+ mice. (A) WTS+ Rag2+/+ and WTS+ Rag2−/−...
Figure S3. Determination of protein concentration of α-syn in C57BL/6 mouse brain, Standard curve of...