<p>Upper and lower 95% confidence intervals for the following time points after dosing shown: Day 7, Day 12, and follow-up (3 days after completion of dosing).</p
<p>(A) Scheme of glycolysis and the PPP with indicated changes of metabolites detected by LC-MS anal...
<p>The decay-curve for 3 mg/kg reaches undetectable levels already after 60 minutes.</p
<p>The values are expressed as the mean±SE. RE, reperfusion period. A 15-min stretch from the high-f...
<p>A) Geometric mean plasma Aβ concentration–time plots over the three dosing intervals (semi-log pl...
Values are means ± SEM. ap dp gp < 0.001 vs. Gly. Li, lithium; Gly, glycerol; Gly+Li, glycerol + lit...
<p>Box and whisker plots show median ±25% within the box and 100% range of all values within whisker...
<p>The group median (squares) rose significantly by day 10 after initiation of treatment (<i>p</i><0...
Baseline corrected geometric mean fold ratio and frequency of response by neutralization assays at f...
<p>Serum TFV (panel A) and PBMC TFV-DP (panel B) concentration versus time plots are shown for the o...
*<p>P-values for two-way comparisons were obtianed by Wilcoxon rank sum tests, and p-values for the ...
<p>Changes from baseline to the indicated time points in estimated creatinine clearance (a), levels ...
Box plots (median, 25% and 75% quartiles) of biomarkers of muscle damage: Creatine phosphokinase (CK...
<p>Time-course of plasma concentrations of GSK933776 by dose: medians (lines) and individual data (d...
<p>Plasma creatinine (A), creatinine clearance (B) and kidney weight/body weight ratio (C) at the en...
Plasma levels of alkaline phosphatase (ALP), total bilirubin, AST and ALT after BDL.</p
<p>(A) Scheme of glycolysis and the PPP with indicated changes of metabolites detected by LC-MS anal...
<p>The decay-curve for 3 mg/kg reaches undetectable levels already after 60 minutes.</p
<p>The values are expressed as the mean±SE. RE, reperfusion period. A 15-min stretch from the high-f...
<p>A) Geometric mean plasma Aβ concentration–time plots over the three dosing intervals (semi-log pl...
Values are means ± SEM. ap dp gp < 0.001 vs. Gly. Li, lithium; Gly, glycerol; Gly+Li, glycerol + lit...
<p>Box and whisker plots show median ±25% within the box and 100% range of all values within whisker...
<p>The group median (squares) rose significantly by day 10 after initiation of treatment (<i>p</i><0...
Baseline corrected geometric mean fold ratio and frequency of response by neutralization assays at f...
<p>Serum TFV (panel A) and PBMC TFV-DP (panel B) concentration versus time plots are shown for the o...
*<p>P-values for two-way comparisons were obtianed by Wilcoxon rank sum tests, and p-values for the ...
<p>Changes from baseline to the indicated time points in estimated creatinine clearance (a), levels ...
Box plots (median, 25% and 75% quartiles) of biomarkers of muscle damage: Creatine phosphokinase (CK...
<p>Time-course of plasma concentrations of GSK933776 by dose: medians (lines) and individual data (d...
<p>Plasma creatinine (A), creatinine clearance (B) and kidney weight/body weight ratio (C) at the en...
Plasma levels of alkaline phosphatase (ALP), total bilirubin, AST and ALT after BDL.</p
<p>(A) Scheme of glycolysis and the PPP with indicated changes of metabolites detected by LC-MS anal...
<p>The decay-curve for 3 mg/kg reaches undetectable levels already after 60 minutes.</p
<p>The values are expressed as the mean±SE. RE, reperfusion period. A 15-min stretch from the high-f...