HCV infection is associated with higher CD68⁺CD80⁺ and CD68⁺CD86⁺ cell frequency in the lobular areas when compared to the portal areas of the liver.

<p>Biopsies from HCV-infected and control individuals were stained as described in the methods. (<b>A</b>) CD68⁺CD80⁺, (<b>B</b>) CD68⁺CD86⁺ and (<b>C</b>) CD68⁺PD-L1⁺ cell count in the lobular and portal areas of the liver of control individuals. (<b>D</b>) CD68⁺CD80⁺, (<b>E</b>) CD68⁺CD86⁺ and (<b>F</b>) CD68⁺PD-L1⁺ cell count and (<b>G</b>) CD68⁺CD80⁺ and (<b>H</b>) CD68⁺CD86⁺ cell percentage in the lobular and portal areas of the liver of HCV-infected patients.