Preparation of Phospholipid Vesicle-Templated Calcium Phosphate Nanostructures and Their Cytocompatibility

Calcium phosphate (CP) nanostructure formation using a phospholipid vesicle (PV) template was investigated in a simulated body fluid. The CP nanoshells surrounding a PV/water core (diameter: 194 nm) were successfully prepared to show the hybrid nanostructures. The lyophilized cast films of the nanohybrids exhibited the CP/PV arrangements at nanometer scales as well as osteoblast-like cell adhesion/proliferation, suggesting cytocompatible nanohybrid structures