Additional file 4: Figure S2. of The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations

Alignment of L1 ORF2 endonuclease domains from several orders within the Supraprimate clade of mammals. The amino acid sequence of the endonuclease domains of species from various mammalian orders were aligned using the Clustal W method. Residues conserved relative to the human L1 endonuclease sequence are shaded in red. Boxes indicate putative phosphorylation sites of interest. (PNG 13086Â kb