<p>Using a single dose of 10 μM of the test compound against the NCI 60 cell lines. Zero on the X-axis represents the mean percentage of growth of the tested cell lines. The percentage of growth of each cell line relative to the mean is represented by a horizontal bar extending to the right side indicating more sensitivity or to the left side indicating less sensitivity.</p
<p>A, GI<sub>50</sub> (in µM) of GDC-0941 for 60 cell lines are ordered from lowest to highest, with...
<p>+ - Viable cells in the range of 80%–90% ; ++ - Viable cells in the range of 50%–60% ; +++ - Viab...
<p>Columns filled with black, gray and white represent OAR19, OAR22 and OAR27, respectively. The cel...
<p>X-axis represents log<sub>10</sub> values (Molar) of the tested compound. Y-axis represents perce...
<p>X-axis represents log<sub>10</sub> values (Molar) of the tested compound. Y-axis represents perce...
PND cytotoxic concentration 50% (CC50) and selective cytotoxic index (SCI) on a panel of human cell ...
<p>1×10∧3 bulk of tumor cells or CSLCs plated in 5 replicas into 96-well plates were challenged for ...
<p>1×10∧3 bulk of tumor cells or CSLCs plated in 5 replicas into 96-well plates were challenged for ...
<p>Cytotoxic activity against HeLa cell line, calculated for all samples tested.</p
<p>Four cell lines were selected from the exquisitely sensitive group (IC50 g <10 nM), three from th...
<p>Cytotoxic activity against KB cell line, calculated for all samples tested.</p
Flow cytometric evaluation of human NCI- H460 NSCLC cells exposed to 3d and reference antitumor drug...
<p>A panel of 59 human tumor cell lines of diverse tumor entities was included in a NCI screen. This...
<p>The better cytotoxicity of each compound against nine cells was highlighted.</p
<p>The inhibition rates of 25 NSCLC cell lines transfected with Ad-REIC compared to Ad-LacZ are show...
<p>A, GI<sub>50</sub> (in µM) of GDC-0941 for 60 cell lines are ordered from lowest to highest, with...
<p>+ - Viable cells in the range of 80%–90% ; ++ - Viable cells in the range of 50%–60% ; +++ - Viab...
<p>Columns filled with black, gray and white represent OAR19, OAR22 and OAR27, respectively. The cel...
<p>X-axis represents log<sub>10</sub> values (Molar) of the tested compound. Y-axis represents perce...
<p>X-axis represents log<sub>10</sub> values (Molar) of the tested compound. Y-axis represents perce...
PND cytotoxic concentration 50% (CC50) and selective cytotoxic index (SCI) on a panel of human cell ...
<p>1×10∧3 bulk of tumor cells or CSLCs plated in 5 replicas into 96-well plates were challenged for ...
<p>1×10∧3 bulk of tumor cells or CSLCs plated in 5 replicas into 96-well plates were challenged for ...
<p>Cytotoxic activity against HeLa cell line, calculated for all samples tested.</p
<p>Four cell lines were selected from the exquisitely sensitive group (IC50 g <10 nM), three from th...
<p>Cytotoxic activity against KB cell line, calculated for all samples tested.</p
Flow cytometric evaluation of human NCI- H460 NSCLC cells exposed to 3d and reference antitumor drug...
<p>A panel of 59 human tumor cell lines of diverse tumor entities was included in a NCI screen. This...
<p>The better cytotoxicity of each compound against nine cells was highlighted.</p
<p>The inhibition rates of 25 NSCLC cell lines transfected with Ad-REIC compared to Ad-LacZ are show...
<p>A, GI<sub>50</sub> (in µM) of GDC-0941 for 60 cell lines are ordered from lowest to highest, with...
<p>+ - Viable cells in the range of 80%–90% ; ++ - Viable cells in the range of 50%–60% ; +++ - Viab...
<p>Columns filled with black, gray and white represent OAR19, OAR22 and OAR27, respectively. The cel...