<p>Average type 1 error rates of the statistic for testing interaction between two genes with marginal effect at one gene consisting only rare variants with 5 traits over randomly selected 50,000 pairs of genes from the whole exome.</p
Statistical interactions are a common component of data analysis across a broad range of scientific ...
<p>The number of significant interactions observed is less than one might expect by chance.</p><p>P ...
Article first published online: 30 APR 2013Genome-wide association studies have been successful in i...
<p>Average type 1 error rates of the statistic for testing interaction between two genes with margin...
<p>The rows highlighted in bold report type I error rates of the procedures after SNP genotype was r...
<p>TAS denotes the number of trait associated SNPs. Machine learning test is based on ensemble learn...
<p>Averaged over 100 simulated data in <i>Scenario</i> 1 for two set of gene effect sizes . The top ...
<p>Testing Accuracy for different combinations: single locus, 63.7 %; two locus, 65.1%; three locus,...
Background: We investigated the influence of genotyping errors on the type I error rate and empirica...
<p>Empirical type I error rates at the significance level of 0.05 based on 100 SNPs.</p
Abstract Background We investigated the influence of genotyping errors on the type I error rate and ...
Objectives: It is well known that genotyping error adversely affects the power of genetic case-contr...
<p>Genotype error rates according to reference population when a) 1% or b) 20% of genotypes were mas...
<p>Empirical type I error rates at the significance level of 0.05 based on 10 SNPs.</p
Background: Spurious associations between single nucleotide polymorphisms and phenotypes are a major...
Statistical interactions are a common component of data analysis across a broad range of scientific ...
<p>The number of significant interactions observed is less than one might expect by chance.</p><p>P ...
Article first published online: 30 APR 2013Genome-wide association studies have been successful in i...
<p>Average type 1 error rates of the statistic for testing interaction between two genes with margin...
<p>The rows highlighted in bold report type I error rates of the procedures after SNP genotype was r...
<p>TAS denotes the number of trait associated SNPs. Machine learning test is based on ensemble learn...
<p>Averaged over 100 simulated data in <i>Scenario</i> 1 for two set of gene effect sizes . The top ...
<p>Testing Accuracy for different combinations: single locus, 63.7 %; two locus, 65.1%; three locus,...
Background: We investigated the influence of genotyping errors on the type I error rate and empirica...
<p>Empirical type I error rates at the significance level of 0.05 based on 100 SNPs.</p
Abstract Background We investigated the influence of genotyping errors on the type I error rate and ...
Objectives: It is well known that genotyping error adversely affects the power of genetic case-contr...
<p>Genotype error rates according to reference population when a) 1% or b) 20% of genotypes were mas...
<p>Empirical type I error rates at the significance level of 0.05 based on 10 SNPs.</p
Background: Spurious associations between single nucleotide polymorphisms and phenotypes are a major...
Statistical interactions are a common component of data analysis across a broad range of scientific ...
<p>The number of significant interactions observed is less than one might expect by chance.</p><p>P ...
Article first published online: 30 APR 2013Genome-wide association studies have been successful in i...