ORs for association between colorectal cancer risk and total cholesterol measured at different time intervals before colorectal cancer diagnosis, among statin nonusers (<i>n</i> = 15,052 cases; <i>n</i> = 46,043 controls).

<p>^a Last total cholesterol value measured in each specified time window prior to the index date of colorectal cancer diagnosis. ^b Adjusted for obesity (BMI ≥ 30 kg/m²), ever smoking, chronic use of aspirin or NSAIDs, hormone replacement therapy, alcohol consumption, diabetes mellitus, performance of bowel screening, and non-statin cholesterol-lowering medication. ^c Per 1 mmol/L increase in serum total cholesterol.