Organic selenium compounds: Synthesis and reactions of some new 7-alkyl-8-selenotheophyllines

<p>A simple and mild synthesis of selenotheophyllines is described based on the reaction of 7-alkyl-8-chlorotheophylline with sodium hydrogenselenide followed by reactions with halocompounds such as chloroacetonitrile, ethyl chloroacetate, chloroacetamide, and ethyl chloroformate. Elemental analysis, infrared, ¹H NMR, ¹³C NMR, and mass spectral data confirmed the structure of the newly synthesized compounds.