Cellular Responses induced by the vaccination regimens including Ad5HVR2 modified vectors.

<p>CB6F1/J (n = 10 per group) mice received the regimens described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0154819#pone.0154819.g002" target="_blank">Fig 2</a>. PBMC derived from mice whole blood were obtained 5 days after the final immunization and were processed by flow cytometry, <b>(A)</b> CD8+ T cells able to recognize the <i>P</i>. <i>yoelii</i> CSP tetramer H-2K^d/SYVPSAEQI. <b>(B)</b> CD4+ T cells expressing CD49d and CD11 as markers for the differentiation of antigen experienced cells. The results are presented as the number of cells present in 10⁶ PBMC. The differences between the groups were analyzed by Kruskal-Wallis test with Dunns post-test, significant statistical differences between the groups are denoted by *(p<0.05) **(p<0.01).