<p>Parameter distributions for passing parameter sets (G) for different model hypotheses (with ADE = antibody dependent enhancement, CI = cross-immunity) for (A) the transmission rate (β<sub>0</sub>), (B) seasonality (β<sub>1</sub>), (C) enhanced susceptibility (α<sub>SUS</sub>), (D) enhanced infectiousness (α<sub>TRANS</sub>), and (E) 1/duration of cross-immunity (ρ). The vertical lines depict the median values for each distribution with the colours indicating the corresponding model hypothesis.</p
<p>(A) Model titres for participant aged 64 y. Parameters in the model are taken from the maximum a ...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
<p><b>). </b><b>A</b>: Relative fitness of the four PVY variants (NN, NH, DN and DH) estimated by th...
<p>Other parameters are as baseline values in <a href="http://www.plosone.org/article/info:doi/10.13...
Parameters for simulations of antibody distributions in vaccinated and control populations for three...
A) Median trajectory of the last compartment of our immune response B) Median trajectory of the infe...
<p>A: cumulative incidence (total number of symptomatic cases) over a 28-year simulation as a functi...
Shown is the best-fit to combined immunological, epidemiological, and evolutionary data available on...
<p>Sixty parameterizations of strain-transcending immunity (strength and duration) were simulated. W...
<p>(A) The epidemic component, a deterministic, compartmental model capturing a single influenza sea...
<p>(A) Simple boosting. In the absence of cross-reactivity and antigenic seniority, if an individual...
These bands represent median values across the set of calibrated parameter values, and the colored b...
grantor: University of TorontoUsing epidemic simulations in randomly mixing and stratifie...
†<p>Rates are given per hour if not otherwise indicated.</p>‡<p>In more complex versions of the mode...
<p>(A) Fit of dynamic host-pathogen model. Grayscale lines represent infection profiles from the <i>...
<p>(A) Model titres for participant aged 64 y. Parameters in the model are taken from the maximum a ...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
<p><b>). </b><b>A</b>: Relative fitness of the four PVY variants (NN, NH, DN and DH) estimated by th...
<p>Other parameters are as baseline values in <a href="http://www.plosone.org/article/info:doi/10.13...
Parameters for simulations of antibody distributions in vaccinated and control populations for three...
A) Median trajectory of the last compartment of our immune response B) Median trajectory of the infe...
<p>A: cumulative incidence (total number of symptomatic cases) over a 28-year simulation as a functi...
Shown is the best-fit to combined immunological, epidemiological, and evolutionary data available on...
<p>Sixty parameterizations of strain-transcending immunity (strength and duration) were simulated. W...
<p>(A) The epidemic component, a deterministic, compartmental model capturing a single influenza sea...
<p>(A) Simple boosting. In the absence of cross-reactivity and antigenic seniority, if an individual...
These bands represent median values across the set of calibrated parameter values, and the colored b...
grantor: University of TorontoUsing epidemic simulations in randomly mixing and stratifie...
†<p>Rates are given per hour if not otherwise indicated.</p>‡<p>In more complex versions of the mode...
<p>(A) Fit of dynamic host-pathogen model. Grayscale lines represent infection profiles from the <i>...
<p>(A) Model titres for participant aged 64 y. Parameters in the model are taken from the maximum a ...
<p>The model was separately fitted to IgM data for DENV1 and DENV2 infections. For immune response p...
<p><b>). </b><b>A</b>: Relative fitness of the four PVY variants (NN, NH, DN and DH) estimated by th...