(A) Heat map highlighting/differentiating the proteasome inhibitors sensitive and insensitive cell lines based on cytotoxicity exhibited by two proteasome inhibitors. (B) Box plot showing the differential expression of protein and phosphoprotein levels (published data) between mitotic inhibitor sensitive and insensitive cell lines. (PDF 104 kb
Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...
CD3 levels in 4T1 tumors grown in wild-type BALB/c mice. Samples were from the experiment shown in F...
IC50 of MEDI3039 and GST-TRAIL in multiple breast cancer cell lines with different subtypes. N.D. = ...
Full heat map showing the 16 TNBC cell lines clustering based on drug responses assessed via cytotox...
Full heat map showing the 16 TNBC cell lines clustering based on drug responses assessed via viabili...
Average DSS calculated for the compounds screened using different viability and toxicity measure. (X...
Combined inhibition of human epidermal growth factor receptor-2 (HER2), p110Îą and Vps34 induces cel...
Percent inhibition data of drug combination matrices in Fig. 7 & S5. (XLSX 64 kb
Cell line specific synergistic drug combination effects. Blue 8 × 8 blue matrices show % viability i...
Table S2. Compounds that were selectively cytotoxic to parental Hs578T cells compared with HSP90i-re...
Characterization of MDA-MB231 and cisplatin-resistant MDA-MB231CisR. MDA-MB231 and cisplatin-resista...
Effect of D11 on NCS-induced cytotoxicity. (a) M059K cells were treated with D11 and NCS as indicate...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...
Figure S3. (A) Heatmap representing the top 25 upregulated and downregulated proteins in untreated c...
Figure S1. The IC50 of the 3 drugs were calculated for the 3 mesenchymal-like cell lines used in thi...
Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...
CD3 levels in 4T1 tumors grown in wild-type BALB/c mice. Samples were from the experiment shown in F...
IC50 of MEDI3039 and GST-TRAIL in multiple breast cancer cell lines with different subtypes. N.D. = ...
Full heat map showing the 16 TNBC cell lines clustering based on drug responses assessed via cytotox...
Full heat map showing the 16 TNBC cell lines clustering based on drug responses assessed via viabili...
Average DSS calculated for the compounds screened using different viability and toxicity measure. (X...
Combined inhibition of human epidermal growth factor receptor-2 (HER2), p110Îą and Vps34 induces cel...
Percent inhibition data of drug combination matrices in Fig. 7 & S5. (XLSX 64 kb
Cell line specific synergistic drug combination effects. Blue 8 × 8 blue matrices show % viability i...
Table S2. Compounds that were selectively cytotoxic to parental Hs578T cells compared with HSP90i-re...
Characterization of MDA-MB231 and cisplatin-resistant MDA-MB231CisR. MDA-MB231 and cisplatin-resista...
Effect of D11 on NCS-induced cytotoxicity. (a) M059K cells were treated with D11 and NCS as indicate...
Effects of AKT and MAPK inhibition on apoptosis in BT474 and MDAMB361 cells. Cell lines grown in 2D ...
Figure S3. (A) Heatmap representing the top 25 upregulated and downregulated proteins in untreated c...
Figure S1. The IC50 of the 3 drugs were calculated for the 3 mesenchymal-like cell lines used in thi...
Figure S2: (A) Hs578T cells were exposed to different concentrations of MEK1/2 inhibitor (AZD6244) a...
CD3 levels in 4T1 tumors grown in wild-type BALB/c mice. Samples were from the experiment shown in F...
IC50 of MEDI3039 and GST-TRAIL in multiple breast cancer cell lines with different subtypes. N.D. = ...