Kinetic analysis of the fluorogenic substrates.

<p>The kinetic parameters (n = 3) were determined for the fluorogenic substrates <b>1</b> and <b>5</b>–<b>14</b> (measured using substrate range of 0.1–8 μM) with caspase-3 and caspase-7. Substrate <b>4</b> or the d-amino acids containing <b>15</b>–<b>24</b> were not cleaved by either enzyme.