GO terms inferred to diseases via gene inference networks.

<p>(A) The "Diseases" data-tab on CTD’s webpage for the GO-BP term “G-protein coupled receptor signaling pathway” lists human pathologies inferred to this GO term, including a connection to obesity made by an inference network of 22 genes (red double arrow). (B) A schematic outlines how this GO term is directly annotated to these 22 genes (by external databases) which, in turn, have also been directly associated with obesity independently by CTD biocurators from the literature, allowing the GO term to be inferred (dotted black arrow) to the disease. (C) The files for "GO-Disease-Gene Inference Networks" are freely available from CTD's "Data Downloads" page and can be retrieved in a variety of formats.