Additional file 3: Figure S3. of Effects of Usag-1 and Bmp7 deficiencies on murine tooth morphogenesis

Difference in mandibular morphology between respective genotypes in Bmp7 or Usag-1-LacZ knock-in mice. (A) Wild-type mouse (ICR) mandible at 2 months after birth with locations of landmarks used to analyze the morphological differences between respective genotypes. Linear distances between the identifiable landmarks were measured. a: inferior-most point on the incisor alveolar rim, b: anterior point on the molar alveolar rim, c: inferior-most point on border of the ramus inferior to incisor alveolar, d: mandibular angle. (B) Difference in mandibular morphology between WT and Bmp7+/− mice. We analyzed a total of 6 WT and 6 Bmp7+/− samples in adult Bmp7-LacZ knock-in (ICR) mice at 2 months after birth. Statistical significance was determined by the Mann–Whitney U test. (C) Difference in the mandibular morphology among WT, Usag-1+/−, and Usag-1−/− mice. We analyzed a total of 6 individual genotypes in adult Usag1-LacZ knock-in (C57BL/6) mice at 3 months after birth. Statistical significance was determined using a Kruskal-Wallis test and a Steel-Dwass test for multiple comparisons. *P < 0.05. (TIF 3530 kb