Induction of conidiation-related genes during the initial stage of sexual development.

<p>(A) Venn diagrams illustrating the overlap between upregulated (A) or downregulated (B) wild-type-specific genes (blue circle, WT-1 d/<i>abaA</i>-1 d) and differentially expressed genes after sexual induction in the wild-type strain (green circle for downregulated genes, WT-24 h/WT-2 h < 2; orange circle for upregulated genes, WT-24 h/WT-2 h > 2). (C) Expression profiles of clustered groups including the conidiation-specific genes <i>WETA</i> and <i>ABAA</i>. Fuzzy clustering categorized 933 upregulated wild-type-specific genes into 10 groups. The genes included in groups 3 and 9 showed similar expression patterns during conidiation with <i>WETA</i> and <i>ABAA</i>, respectively. (D) The Venn diagram illustrating the overlap between the <i>WETA</i>- and <i>ABAA</i>-related genes (blue circle) and the upregulated genes after sexual induction in the wild-type strain (orange circle). Wild-type-specific genes (WT-1 d/<i>abaA</i>-1 d) represent differentially expressed genes in the wild-type strain compared to the <i>abaA</i> mutant 1 day after sexual induction. Genes that were differentially expressed 24 h after sexual induction compared to the uninduced condition (2 h) represent differentially expressed genes after sexual induction [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0155671#pone.0155671.ref030" target="_blank">30</a>].