Inflammatory responses to RhCMV<i>gagfliC</i>Δ196–378 in RhCMV macaques.

<p><b>(A)</b> Eight RhCMV sero-negative macaques were inoculated with RhCMV, RhCMV<i>gag</i>, or RhCMV<i>gagfliC</i>Δ196–378 and skin biopsies were collected seven days post-infection at the site of inoculation. <b>(B)</b> RhCMV sero-positive macaques were infected with either RhCMV<i>gag</i> (six macaques) or RhCMV<i>gagfliC</i>Δ196–378 (five macaques) and skin biopsies were collected at the site of inoculation seven days post-infection. Slides generated from the skin biopsies were stained by H&E and scored for inflammatory cell infiltrates. Charts indicate the observed inflammation with 0 (white) representing no observed inflammation, 1 (light blue) representing mild inflammation, 2 (medium blue) representing moderate inflammation, and 3 (darkest blue) representing severe inflammation.