Statistical properties of cell cycle progression.

<p>Experimental observations for wild-type cells [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153738#pone.0153738.ref038" target="_blank">38</a>] (blue bars) are compared to simulations from four different cases of our model: the full stochastic SCM (red bars), the stochastic SCM without the mRNA-inherited noise term (green bars), the deterministic SCM with “extrinsic” noise only (magenta bars), and the completely deterministic SCM (black bars). <i>T</i>_c is cell cycle duration (min) = <i>T</i>_G1 + <i>T</i>_b = <i>T</i>₁ + <i>T</i>₂ + <i>T</i>_b. <i>T</i>₁ is the duration from cell birth to Start (min), which we identify with SBF reaching 50% of its maximum value. <i>T</i>₂ is the period from Start to bud emergence (min), which we identify with [BUD]_n = 1. <i>T</i>_G1 = <i>T</i>₁ + <i>T</i>₂ = duration of the “unbudded phase” (min). <i>T</i>_b is the duration of the “budded phase,” from bud emergence to the next cell division (min). <i>V</i>_birth is cell size at birth (fL). Asterisks indicate unreported data.