Additional file 5. H3K9 methyltransferase knockdown validation. qRT-PCR of H3K9 methyltransferase expression levels in cells transduced with H3K9 methyltransferase shRNAs, 3 days after transduction. Results are relative to the average of housekeeping genes Hmbs and Hprt, then normalised to Nons. n = 3, mean ± s.e.m. One way ANOVA with Dunnett correction for multiple testing. * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.001
The SET Domain Bifurcated Histone Lysine Methyltransferase 1 (SETDB1) is a prominent member of the S...
Setdb1/Eset, a histone H3-lysine 9 (H3K9)-specific methyltransferase, interacts with various transcr...
(A) Genome browser view of H3K9me2 abundance at ONSEN in Col-0 and the SUVH4, SUVH5, and SUVH6 loss-...
Additional file 14. Expression of key genes from ES cell RNA-seq. The expression of Setdb1, all know...
Additional file 17. Primer sequences. List of cloning and qRT-PCR primers used in this study
Additional file 12. RNA-seq data confirms correct behaviour of the Xist∆A allele. Reads at Xist are ...
Additional file 6. Failure of in vivo XCI in Setdb1gt/gt female embryos. a. Genomic location (mm10) ...
Additional file 16. LTR repeats are deregulated upon Setdb1 depletion. Analysis of repeat class expr...
BACKGROUND: The presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome...
AbstractCovalent modifications of chromatin have emerged as key determinants of the genome's transcr...
<p>A. Representative view of genes that gain ectopic H3K9m2 and non-CG methylation. Left panel: IGB ...
<p>SETDB1 is a H3K9 methyltransferase involved in transcriptional silencing with a catalytic SET dom...
La méthylation de la lysine 9 de l’histone 3 (H3K9), établie par les lysine méthyltransférases (KMTs...
SETDB1 (SET Domain Bifurcated histone lysine methyltransferase 1) is a key lysine methyltransferase ...
(A) DNA methylation status of the promoter regions of Stra8 and Sycp3 in control (4OHT−) and Ring1a/...
The SET Domain Bifurcated Histone Lysine Methyltransferase 1 (SETDB1) is a prominent member of the S...
Setdb1/Eset, a histone H3-lysine 9 (H3K9)-specific methyltransferase, interacts with various transcr...
(A) Genome browser view of H3K9me2 abundance at ONSEN in Col-0 and the SUVH4, SUVH5, and SUVH6 loss-...
Additional file 14. Expression of key genes from ES cell RNA-seq. The expression of Setdb1, all know...
Additional file 17. Primer sequences. List of cloning and qRT-PCR primers used in this study
Additional file 12. RNA-seq data confirms correct behaviour of the Xist∆A allele. Reads at Xist are ...
Additional file 6. Failure of in vivo XCI in Setdb1gt/gt female embryos. a. Genomic location (mm10) ...
Additional file 16. LTR repeats are deregulated upon Setdb1 depletion. Analysis of repeat class expr...
BACKGROUND: The presence of histone 3 lysine 9 (H3K9) methylation on the mouse inactive X chromosome...
AbstractCovalent modifications of chromatin have emerged as key determinants of the genome's transcr...
<p>A. Representative view of genes that gain ectopic H3K9m2 and non-CG methylation. Left panel: IGB ...
<p>SETDB1 is a H3K9 methyltransferase involved in transcriptional silencing with a catalytic SET dom...
La méthylation de la lysine 9 de l’histone 3 (H3K9), établie par les lysine méthyltransférases (KMTs...
SETDB1 (SET Domain Bifurcated histone lysine methyltransferase 1) is a key lysine methyltransferase ...
(A) DNA methylation status of the promoter regions of Stra8 and Sycp3 in control (4OHT−) and Ring1a/...
The SET Domain Bifurcated Histone Lysine Methyltransferase 1 (SETDB1) is a prominent member of the S...
Setdb1/Eset, a histone H3-lysine 9 (H3K9)-specific methyltransferase, interacts with various transcr...
(A) Genome browser view of H3K9me2 abundance at ONSEN in Col-0 and the SUVH4, SUVH5, and SUVH6 loss-...