ADR or TSP1 treatment induced human podocyte apoptosis and actin cytoskeleton disorganization.

<p>Human podopcytes were treated with ADR (20μg/ml) or TSP1 (5μg/ml) for 24 hours. Then, TUNEL and F-actin staining was performed (A). TUNEL positive cells were calculated (B). Caspase 3 activity in cell lysates was measured (C). Data are presented as mean ± SE (n = 3 individual experiments). ***, <i>P</i> <0.001 vs. control.