Metabolic pathway involved in the conversion of propionate to 3-hydroxypropionate in recombinant <i>E</i>. <i>coli</i> strains.

<p>The enzymes in bold are overexpressed, while disrupted pathway steps are indicated by the bold “×” symbols. MC cycle: methylcitrate cycle; TCA cycle: tricarboxylic acid cycle; PCT: propionate CoA-transferase; PACD: propionyl-CoA dehydrogenase; HPCD: 3-hydroxypropionyl-CoA dehydratase; YgfH: propionyl-CoA: succinate-CoA transferase; PrpC: methylcitrate synthase.