UVB causes systemic immunosuppression of host.

<p>Three groups of mice were treated as follows: a control group that was not UVB irradiated (FVB-UVB, White bars, n = 3), UVB-irradiated group (FVB+UVB, Striped bars, n = 6) and UVB-irradiated group in which ears were shielded from UVB exposure [FVB+UVB (ears shielded), Black bars]. Ear thickness reported as the average of the difference between DNCB-challenged (left) and unchallenged (right) ears four days post challenge. SEM refers to standard error in measurement computed by measuring standard deviation. DTH measured by the change in thickness of the ear (ΔEar) was found to be statistically significant between UVB-treated mice and non-irradiated control mice (student t-test, <i>p<0</i>.<i>005</i>, <i>two-sided)</i> for both UVB-treated groups.