Effects of collagen polymerization on SMPC proliferation and viability.

<p>Representative SEM images depicting the topology of surfaces coated with fibrillar (A) or non-fibrillar collagen preparations (B, scale bars are 10 μm). BMCs cultured for 10 d in 10% α-MEM, and then re-plated onto substrates as indicated, at 24, 48 and 72 h, cell density (C) and BrdU incorporation (D) were measured. Indices of Apoptosis were assessed in SMPCs (E) and primary cultures of murine SMCs (F) by Annexin V/PI co-staining. (* <i>p</i> < 0.05, ** <i>p</i> < 0.01, (C, D, <i>n</i> = 4), (E, F, <i>n</i> = 3), Tukey-Kramer multiple comparisons test).