Mathematical model fit to quantitative shedding rate and episode rate.

<p>Ten mathematical model simulations of HSV-2 shedding (thin colored lines) in reference to empirical shedding data (median marked with black dot and 95% CI with black horizontal bars). Quantitative shedding per swab for <b>(A)</b> HIV negative, and HIV positive men with <b>(B)</b> CD4+ T-cells >500/μL, <b>(C)</b> 200-499/μL and <b>(D)</b> <200/μL.