Colonic immune cell responses in <i>C</i>. <i>jejuni</i> strain 81–176 infected gnotobiotic mice lacking IL-23p19, IL-22 or IL-18.

<p>The average number of colonic epithelial cells positive for <b>(A)</b> CD3 (T Lymphocytes), <b>(B)</b> FOXP3 (Regulatory T Cells, Tregs), <b>(C)</b> B220 (B Lymphocytes), and <b>(D)</b> F4/80 (Macrophages / Monocytes) from at least six high power fields (HPF, 400x magnification) per animal was determined microscopically in immunohistochemically stained colonic paraffin sections at day (d) 8 (black circles) postinfection. Naive (N) mice served as uninfected controls (white circles). Medians (black bars), level of significance (p-value) determined by Mann-Whitney U test, and numbers of analyzed animals (in parentheses) are indicated. Data were pooled from four independent experiments.