Effect of PD solutions on <i>P. aeruginosa</i> and CNS planktonic cells.

<p>Mean log CFU/mL after 24 h exposure to PD solutions was used for the generation of the heat map. The strains are indicated on the right (Pa, P. aeruginosa; Se, S. epidermidis, Scc, S. caprae/capitis; Sha, S. haemolyticus; Sho, S. hominis). Strains derived from catheters of patients with infection are indicated with an asterisk. Main strains clusters are identified as group 1 (G1) and group 2 (G2). The conventional and biocompatible (bicarbonate, bicarbonate/lactate, icodextrin) PD solutions are indicated on the bottom, as well as the growth controls: positive (C+, TSB culture medium) and negative (C-, saline). The initial inoculum concentration was of ~1 × 107 CFU/mL (7 log CFU/mL). Dendrograms across the top and left of the heat map show the relationship between PD solutions and strains, respectively. Distance values are depicted by the gradient colour ranging from green (lowest value) to red (highest value).