Comparison of brain networks.

<p><b>a</b>. The group-averaged structural networks for the controls (left) and type 2 diabetes (right). Nodes (spheres) represent cortical regions based on the brain parcellation, in which the sizes and colors indicate the numbers of connections involving the brain regions. The connections between nodes reflect the reconstructed white matter pathways. The networks vary from person to person, and the lines displayed represent the connections found in at least 75% of the participants. <b>b</b>. Structural network properties of the two groups. Middle-aged people with chronic hyperglycemia had a longer path length and lower efficiency than the controls (*FDR corrected <i>P</i><0.05 with 10,000 permutation tests), suggesting impaired network integration in the brains of type 2 diabetes.