<p>Estimates of cGVHD & relapse free survival (cGRFS, left panel), relapse-free survival (RFS, middle panel) and overall survival (OS, right panel) are presented across discovery [A], validation [B] and combined [C] cohorts. A multivariate Cox Proportional Hazards Regression at the end of follow-up revealed a significantly poorer (p-values <0.05) cGRFS in both discovery and validation cohorts in addition to a combined cohort (discovery + validation) when KIR genotype mismatched donors were used.</p
<p>A total of 42 KIR gene profiles were identified (panel A). Genotype ID number reported are those ...
<p>P: Fisher exact test; P<sup>n</sup>: The P values of statistically significant differences were t...
<p><i>KIR2DS3</i> was genotyped in our cohort by PCR-SSP. The carrier frequency of <i>KIR2DS3</i> in...
BackgroundAllogeneic hematopoietic cell transplantation (HCT) can be curative for many hematologic d...
<p>OS Kaplan-Meier survival curves (truncated at 80months) of patients stratified on patients with t...
Natural killer (NK) cell alloreactivity, which may contribute to the graft-versus-leukemia (GVL) eff...
Objectives: The goal of this study was to explore the role of NK cell alloreaction in predicting pro...
Abstract: In this retrospective study, the influence of donor and recipient KIR-gene content and the...
<p>*: Combination of Group C and any cognate inhibitory KIR</p><p>Comparison of KIR and KIR ligand g...
<p><b>(A)</b> Cumulative incidence of grade III-IV GVHD. <b>(B)</b> Cumulative incidence of relapse....
AbstractMatching for HLA class I alleles, including HLA-C, is an important criterion for outcome of ...
Donor killer immunoglobulin-like receptor (KIR) genotypes are associated with relapse protection and...
Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity mediated t...
This study was purposed to investigate the role of NK-alloreactivity and donor-inhibiting or activat...
<p>Abbreviation: FYS, five-year survival rate; HR, hazard ration; CI, confidence interval.</p>a<p>De...
<p>A total of 42 KIR gene profiles were identified (panel A). Genotype ID number reported are those ...
<p>P: Fisher exact test; P<sup>n</sup>: The P values of statistically significant differences were t...
<p><i>KIR2DS3</i> was genotyped in our cohort by PCR-SSP. The carrier frequency of <i>KIR2DS3</i> in...
BackgroundAllogeneic hematopoietic cell transplantation (HCT) can be curative for many hematologic d...
<p>OS Kaplan-Meier survival curves (truncated at 80months) of patients stratified on patients with t...
Natural killer (NK) cell alloreactivity, which may contribute to the graft-versus-leukemia (GVL) eff...
Objectives: The goal of this study was to explore the role of NK cell alloreaction in predicting pro...
Abstract: In this retrospective study, the influence of donor and recipient KIR-gene content and the...
<p>*: Combination of Group C and any cognate inhibitory KIR</p><p>Comparison of KIR and KIR ligand g...
<p><b>(A)</b> Cumulative incidence of grade III-IV GVHD. <b>(B)</b> Cumulative incidence of relapse....
AbstractMatching for HLA class I alleles, including HLA-C, is an important criterion for outcome of ...
Donor killer immunoglobulin-like receptor (KIR) genotypes are associated with relapse protection and...
Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity mediated t...
This study was purposed to investigate the role of NK-alloreactivity and donor-inhibiting or activat...
<p>Abbreviation: FYS, five-year survival rate; HR, hazard ration; CI, confidence interval.</p>a<p>De...
<p>A total of 42 KIR gene profiles were identified (panel A). Genotype ID number reported are those ...
<p>P: Fisher exact test; P<sup>n</sup>: The P values of statistically significant differences were t...
<p><i>KIR2DS3</i> was genotyped in our cohort by PCR-SSP. The carrier frequency of <i>KIR2DS3</i> in...