<p>mRNAs are displayed according to expression calculated from mRNA-sequencing (FPKM, fragments per kilobase of exon per million mapped fragments). <i>Red</i>, PLCβ1b; <i>blue</i>, PLCβ1a; <i>black</i>, blank control. Values are mean ± SEM, n = 6. No comparisons to blank control were significant at FDR<0.1 (according to DESeq). Acta1, α-skeletal actin; Actc1, α-cardiac actin; Atp2a2, SERCA2a; Myh6, α-myosin heavy chain; Myh7, β-myosin heavy chain; Nppa, atrial natriuretic peptide; Nppb, natriuretic peptide B; Pln, phospholamban.</p
textabstractCardiac hypertrophy is the response of the heart to an increased workload. After myocard...
The pathogenesis of cardiac left ventricular hypertrophy and failure is poorly defined due to the co...
Although both physiological hypertrophy (PHH) and pathological hypertrophy (PAH) of the heart have s...
In the mammalian heart, the development of cardiac hypertrophy is a common feature that normally pre...
AbstractIn the mammalian heart, the development of cardiac hypertrophy is a common feature that norm...
<p>Bar plot showing the expression levels for some of the canonical hypertrophy markers in ET1-CM wh...
Cardiac hypertrophy is when heart muscles thicken as an adaptive response to several stimuli. Prolon...
<p>qPCR analysis showing mRNA expression of <i>Nppa</i> (A), <i>Nppb</i> (B), <i>Myh7</i> (C), <i>Co...
<p>A) ANP (n = 12–16 per group), B) BNP (n = 12–16 per group), C) GDF15 (n = 12–16 per group), D) sk...
Cardiac hypertrophy is an important and independent risk factor for the development of cardiac myopa...
<p>Relative quantities normalized to the mean wildtype are shown. Abbreviations are: ANP, natriureti...
Transitions in sarcomeric a-actin and cardiac myosin heavy chain (MHC) gene expression have been use...
<p>(A) The actin isoforms, the microfilaments component; desmin, the intermediate filaments componen...
Abstract—Increased ventricular expression of several genes, including atrial natriuretic factor (ANF...
We have previously described a quantitative method for measuring mRNA abundance in endomyocardial bi...
textabstractCardiac hypertrophy is the response of the heart to an increased workload. After myocard...
The pathogenesis of cardiac left ventricular hypertrophy and failure is poorly defined due to the co...
Although both physiological hypertrophy (PHH) and pathological hypertrophy (PAH) of the heart have s...
In the mammalian heart, the development of cardiac hypertrophy is a common feature that normally pre...
AbstractIn the mammalian heart, the development of cardiac hypertrophy is a common feature that norm...
<p>Bar plot showing the expression levels for some of the canonical hypertrophy markers in ET1-CM wh...
Cardiac hypertrophy is when heart muscles thicken as an adaptive response to several stimuli. Prolon...
<p>qPCR analysis showing mRNA expression of <i>Nppa</i> (A), <i>Nppb</i> (B), <i>Myh7</i> (C), <i>Co...
<p>A) ANP (n = 12–16 per group), B) BNP (n = 12–16 per group), C) GDF15 (n = 12–16 per group), D) sk...
Cardiac hypertrophy is an important and independent risk factor for the development of cardiac myopa...
<p>Relative quantities normalized to the mean wildtype are shown. Abbreviations are: ANP, natriureti...
Transitions in sarcomeric a-actin and cardiac myosin heavy chain (MHC) gene expression have been use...
<p>(A) The actin isoforms, the microfilaments component; desmin, the intermediate filaments componen...
Abstract—Increased ventricular expression of several genes, including atrial natriuretic factor (ANF...
We have previously described a quantitative method for measuring mRNA abundance in endomyocardial bi...
textabstractCardiac hypertrophy is the response of the heart to an increased workload. After myocard...
The pathogenesis of cardiac left ventricular hypertrophy and failure is poorly defined due to the co...
Although both physiological hypertrophy (PHH) and pathological hypertrophy (PAH) of the heart have s...