Additional file 9: of Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer

Point mutations from exome-sequencing. Point mutations, sequencing reads and mutation frequency in tamoxifen-resistant cells (Resistant Reference Reads, Resistant Variant Reads, Resistant Variant Frequency) compared to their parental cell lines (Parental Reference Reads, Parental Variant Reads, Parental Variant Frequency) revealed by exome-sequencing. Sample ID, chromosome, position, reference and variant base, affected gene, effect, effect impact, and p-values are also indicated. (XLSX 250Â kb