Additional file 8: Figure S6. of Regulation of distinct branches of the non-canonical Wnt-signaling network in Xenopus dorsal marginal zone explants

Dynamic expression of pbk and rab11fip5. Maternally expressed pbk mRNA (A) is localized at the animal half of the embryo. At gastrula stages no enrichment of pbk transcripts at distinct regions is visible. However, half-dissected embryos revealed pbk expression mainly in the mesoderm. During the neurula stage, pbk mRNA is localized mainly in the developing CNS including the eyes. This localization persists in the tailbud stage. Transversal sections (1 and 2) indicate enriched pbk mRNA in the dorsal part of the neural tube (arrows). Until gastrula stages rab11fip5 expression is similar to pbk expression: enriched in the animal half and later concentrated in the mesoderm. From the early neurula stage onward rab11fip5 is enriched the anterior neuroectoderm (sections 1 and 2). From the late neurula stage onward, an additional ring shaped expression domain is found around the cement gland (section 3, arrow). NT: neural tube, NC: notochord, CG: cement gland. (TIF 10234Â kb