Changes in levels of expression of Beclin-1 in GSC and SNB19 cells corresponded with the miR-30e target prediction.

<p>(A) RT-PCR and Western blotting to determine relative expression of Beclin-1 mRNA and protein, respectively, in GSC and SNB19 cells after treatment with SS, as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0158537#pone.0158537.g001" target="_blank">Fig 1</a> legend. (B) Quantitative analysis of Beclin-1 mRNA and protein from three independent experiments to present as bar diagrams. Significant difference between CTL and any treatment was indicated by *<i>P</i> < 0.05 and **<i>P</i> < 0.01. (C) Bioinformatics analysis showing Beclin-1 as a potential target for miR-30e.