Schematic presentation to show inhibition of SS-induced autophagy and induction of apoptosis in glioblastoma cells.

<p>miR-30e inhibited autophagy via degradation of Beclin-1 and induced apoptosis via degradation of AVEN and BIRC6. PAC exerted its anti-cancer activity through activation of caspases. Combination of miR-30e and PAC most effectively inhibited autophagy and augmented apoptosis for controlling growth of glioblastoma cells.